Jessie Nyl & Karen Kresbach

Essential information:
The name of the disease external image rabies.jpg
  • Rabies
The name of the organism that causes the disease.
  • Rabies Virus (RNA Virus)
What kind of organism is it? (Bacteria, virus, type, size, etc.)
  • Virus (family: Rhabdoviruses)
external image rabies_virus.jpg
The effects of the disease (symptoms, target tissues, toxins, complications, etc.).
  • Rabies only affects mammals. They attack the brain and cause inflammation and death.
  • First Symptoms appear one to three months after infection.
  • Early symptoms are similar to the symptoms of the flu and may include fever, headache and general tiredness.
  • The infected person may experience discomfort, numbness or pain at the site of the bite.
  • Later symptoms of rabies can include things like: Anxiety, Confusion, Excitation, Agitation, Hyper salvation, difficult swallowing, insomnia, slight or partial paralysis, hallucinations and hydrophobia (fear of water)
  • Over the next week or so the rabies virus causes encephalitis (inflammation of the brain) and ultimately death.
What treatment is there for the disease?
  • Because there is no cure and death is almost certain after the symptoms start, treatment for rabies involves supportive care. (managing symptoms and making the person comfortable)
  • The preferred method of treatment is 5 shots of human rabies globulin (HRIG) and a single shot of rabies vaccine.
  • The shots must be given within 14 after the initial exposure to be 100% effective.
  • Rinsing the area immediately with a povitone-iodine solution is the best to do. If inaccessible, use soap and wash area for at least 5 minutes.
  • The doses of (HRIG) holds the virus at bay while the body mounts its own immune response with the help of vaccination.
  • The last step is to receive several doses of the rabies vaccine at 0,3,7,14 and 28 days past exposure.
  • Receiving these vaccines ensures that the body continues to actively build antibodies against the virus. It ensures that all traces of it are destroyed by the stimulated antibodies.
  • The key is preventing the virus from taking hold; once this occurs, it is usually fatal.
external image 450_CGY_rabies_vaccine.jpg

How is it transmitted? (Spread)
  • Rabies can only be transmitted in a few ways like: Bites, non-bite exposure and human-to-human transmission.
  • A bite from a rabid animal is the most common form of rabies transmission.
  • Non-bite exposure and human-to-human exposure are both rare.
  • Bites: Infected salva of an animal passed to an uninfected animal through a bite. From the saliva's point of entry, the rabies travels along the nerve cells to the brain. There it multiplies and then moves to the salivary glands.
  • The cycle is repeated when the animal bites a person or another animal.
  • Non-bites Exposure: Rabies transmission from non-bite exposure is rare
  • Scratches, abrasion, open wounds, or mucous membranes contaminated with saliva or other potentially infectious material from a rabid animal, constitute non-bite exposure.
  • Inhalation of aerosolized rabies virus is also a potential non-bite route of exposure, but with the expectation of laboratory workers, most people are unlikely to encounter an aerosol version of the rabies virus.
  • Human-to-human rabies transmission: Rabies that is transmitted from human to human is also extremely rare. The only well documented cases of rabies caused by human-to-human transmission occurred among eight recipients of transplanted corneas and recently among three recipients of solid organs
  • In addition to bite and non-bite exposures inflicted by infected humans could theoretically transmit rabies, but no such case has been documented.

How to prevent the disease? (vaccine, better hygiene, sanitation, or other methods)
  • There are a number of ways to prevent an infection from rabies virus. Some suggestions are important for pet owners, others involve common sense ways to avoid contact with potential rabid animals
  • Pet owners should keep vaccinations current for all dogs, cats and ferrets. That is important not only to keep your pets from getting rabies, but also to provide a barrier of protection for you, should your pet be bitten by a rabid wild animal.
  • Do not let your pet roam.Keep your pet under direct supervision minimizes the chance of them to come in contact with wild animals.
  • Call your local animal control agency to remove any stray animals from your neighborhood, which prevents the chance that your pet might get infected.
  • Spraying or neutering your pet helps to reduce the number of unwanted pets that may not be properly cared for or regularly vaccinated
  • People: can prevent rabies by avoiding direct contact with unfamilar animals
  • Enjoy wild animals at a distance, do not handle, feed, or unintentionally attract wild animals with open garbage cans or litter.
  • Never adopt wild animals or bring them into your home
  • Do not try to nurse sick animals to health. Teach children never to handle unfamiliar animals even if it appears friendly.
  • Seal of heeles that animals might use as entry ways into your home.
  • When travelling abroad, avoid direct contact with wild animals and be especially careful around dogs in developing countries.

References: http://rabies.emedtv.com/rabies/rabies-treatment.htmlhttp://bodyandhealth.canada.com/condition_info_details.asp?disease_id=303http://emedicine.medscape.com/article/785543-overview